Investigating brain activity patterns in Parkinson's disease
Understanding Circuit Dynamics in Parkinson's Disease using Real-Time Neural Control
This study is looking at how certain brain waves affect movement problems in people with Parkinson's disease, and it offers patients a chance to try a new treatment that might help improve their symptoms like stiffness and slow movements.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Minnesota NIH-funded |
| Lab location | 1 site (Minneapolis, United States) |
| Project ID | NIH-10930891 on NIH RePORTER |
What this research studies
This research focuses on understanding how specific brain activity patterns, particularly beta band oscillations, relate to motor symptoms in Parkinson's disease. By using a novel technique called evoked-interference closed-loop deep brain stimulation (eiDBS), researchers aim to manipulate these oscillations in real-time to determine their causal relationship with symptoms like rigidity and bradykinesia. Patients may have the opportunity to participate in this innovative approach, which could lead to improved treatment strategies for managing their condition.
Who could benefit from this research
Good fit: Ideal candidates for participation are individuals diagnosed with Parkinson's disease who experience motor symptoms such as bradykinesia and rigidity.
Not a fit: Patients with Parkinson's disease who do not exhibit significant motor symptoms may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective treatments for managing motor symptoms in Parkinson's disease.
How similar studies have performed: Previous research has shown promise in using deep brain stimulation techniques to manage symptoms in Parkinson's disease, suggesting that this approach may yield valuable insights.
Where this research is happening
Minneapolis, United States
- University of Minnesota — Minneapolis, United States (Active)
Researchers
- Principal investigator: Aman, Joshua E — University of Minnesota
- Study coordinator: Aman, Joshua E
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.