Investigating brain activity and changes related to learning and addiction.
Multiplex Imaging of Brain Activity and Plasticity with Optimized FRET/FLIM-based Sensors
This study is all about exploring how our brain's connections change when we learn new things or deal with challenges like addiction, using special tools to see what's happening in real-time, so we can better understand how our brains work.
Quick facts
| Grant type | U01 cooperative agreement |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Northwestern University NIH-funded |
| Lab location | 1 site (Chicago, UNITED STATES) |
| Project ID | NIH-11005061 on NIH RePORTER |
What this research studies
This research focuses on understanding how neuronal circuits in the brain adapt and change, which is crucial for learning, memory, and conditions like addiction. By developing advanced sensors that can measure brain activity and biochemical signals in real-time, the research aims to visualize these processes in living brains. The approach involves using innovative imaging techniques to track changes in neuronal activity during specific tasks, providing insights into how the brain functions and responds to various stimuli.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals with conditions related to addiction or those interested in the mechanisms of learning and memory.
Not a fit: Patients with severe cognitive impairments or those not able to participate in behavioral tasks may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new treatments for addiction and other neurological conditions by enhancing our understanding of brain plasticity.
How similar studies have performed: Previous research has shown promising results using similar imaging techniques to study brain activity and plasticity, indicating a strong potential for success in this area.
Where this research is happening
Chicago, UNITED STATES
- Northwestern University — Chicago, United States (Active)
Researchers
- Principal investigator: Dombeck, Daniel a — Northwestern University
- Study coordinator: Dombeck, Daniel a
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.