Investigating bone quality in patients with long-standing type 1 diabetes
Bone Quality in Patients with Long-Standing Type 1 Diabetes
This study is looking at how having type 1 diabetes for a long time might affect bone health and the risk of breaking bones, especially in middle-aged and older adults, by comparing their bone strength and quality to those without diabetes.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Colorado Denver NIH-funded |
| Lab location | 1 site (Aurora, UNITED STATES) |
| Project ID | NIH-10907708 on NIH RePORTER |
What this research studies
This research focuses on understanding how long-standing type 1 diabetes affects bone quality and fracture risk. It aims to assess bone mineral density and strength using advanced imaging techniques in individuals with type 1 diabetes compared to matched controls. The study will also explore the impact of chronic high and low blood sugar levels on bone health, particularly in middle-aged and older adults. By examining the microstructure of bones and the role of bone marrow fat, the research seeks to uncover factors that contribute to increased fracture risk in these patients.
Who could benefit from this research
Good fit: Ideal candidates for this research are middle-aged and older adults with a long history of type 1 diabetes.
Not a fit: Patients without a diagnosis of type 1 diabetes or those who are younger than middle age may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved strategies for preventing fractures in patients with type 1 diabetes.
How similar studies have performed: Previous research has indicated that understanding bone quality in diabetes is crucial, but this specific approach to studying bone microstructure in long-standing type 1 diabetes is relatively novel.
Where this research is happening
Aurora, UNITED STATES
- University of Colorado Denver — Aurora, United States (Active)
Researchers
- Principal investigator: Carballido-Gamio, Julio — University of Colorado Denver
- Study coordinator: Carballido-Gamio, Julio
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.