Investigating bone health in HIV-infected women during pregnancy and breastfeeding
Determining Bone Loss and Bone Mineral Density Recovery Following Repeat Pregnancy/Lactation Among HIV Women on ART
This study is looking at how having more than one baby and breastfeeding can impact bone health in women with HIV who are taking medication, and it aims to help these mothers understand how to take care of their bones over time.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Johns Hopkins University NIH-funded |
| Lab location | 1 site (Baltimore, United States) |
| Project ID | NIH-10456636 on NIH RePORTER |
What this research studies
This research examines how repeat pregnancies and breastfeeding affect bone mineral density (BMD) in women living with HIV who are on antiretroviral therapy (ART). By following participants from the PROMISE trial, the study aims to gather data on BMD changes over time and identify factors that influence bone loss and recovery. Participants will undergo assessments to measure their bone health and understand the long-term implications of ART on their skeletal health. The findings could provide valuable insights into managing bone health for HIV-infected mothers.
Who could benefit from this research
Good fit: Ideal candidates for this research are HIV-infected women who have experienced multiple pregnancies and are currently on ART.
Not a fit: Patients who are not HIV-infected or those who have not undergone pregnancy or breastfeeding may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved strategies for maintaining bone health in HIV-infected women during and after pregnancy.
How similar studies have performed: Previous studies have indicated significant changes in bone density among HIV-infected women, suggesting that this research builds on established findings rather than exploring a completely novel area.
Where this research is happening
Baltimore, United States
- Johns Hopkins University — Baltimore, United States (Active)
Researchers
- Principal investigator: Fowler, Mary Glenn — Johns Hopkins University
- Study coordinator: Fowler, Mary Glenn
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.