Investigating body composition and its effects on kidney cancer outcomes
Official title: Body composition and the obesity paradox in clear cell renal cell carcinoma
Funded at Sloan-Kettering Inst Can Research · NIH-10675702 · Data updated 2026-11-12
This study is looking at how different aspects of body composition, not just weight, can impact survival for people with clear cell kidney cancer, using CT scans and tumor samples to find helpful insights for better health recommendations.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Sloan-Kettering Inst Can Research NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project start | August 1, 2019 |
| Project end | July 31, 2025 |
| Funding year | 2023 |
| Award (this year) | $587,431 |
| NIH project number | 5R01CA233885-05 |
| Project ID | NIH-10675702 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals diagnosed with non-metastatic clear cell renal cell carcinoma who have undergone nephrectomy.
✕Less likely to help
Patients with metastatic clear cell renal cell carcinoma or those who have not undergone nephrectomy may not benefit from this research.
What this research studies
This research focuses on clear cell renal cell carcinoma (ccRCC), a serious type of kidney cancer, and aims to understand how body composition, beyond just body mass index (BMI), affects patient prognosis. By analyzing pre-surgical CT scans and tumor samples from a large group of ccRCC patients, the study seeks to identify specific body composition features that may influence survival rates. The goal is to provide insights that could lead to better weight management recommendations and prognostic factors for patients with this cancer.
Why it matters
Potential benefit: If successful, this research could lead to improved treatment strategies and personalized care for kidney cancer patients based on their body composition.
How similar studies have gone: Previous research has indicated that body composition can significantly impact cancer outcomes, suggesting that this approach may yield valuable insights.
Where this research is happening
-
Sloan-Kettering Inst Can Research
New York, United States Active
Researchers
- Principal investigator: Furberg-Barnes, Anna Helena — Sloan-Kettering Inst Can Research
- Study coordinator: Furberg-Barnes, Anna Helena
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.