Investigating body composition and its effects on kidney cancer outcomes

Body composition and the obesity paradox in clear cell renal cell carcinoma

NIH-funded research Sloan-Kettering Inst Can Research · NIH-10675702

This study is looking at how different aspects of body composition, not just weight, can impact survival for people with clear cell kidney cancer, using CT scans and tumor samples to find helpful insights for better health recommendations.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionSloan-Kettering Inst Can Research NIH-funded
Lab location1 site (New York, United States)
Project IDNIH-10675702 on NIH RePORTER

What this research studies

This research focuses on clear cell renal cell carcinoma (ccRCC), a serious type of kidney cancer, and aims to understand how body composition, beyond just body mass index (BMI), affects patient prognosis. By analyzing pre-surgical CT scans and tumor samples from a large group of ccRCC patients, the study seeks to identify specific body composition features that may influence survival rates. The goal is to provide insights that could lead to better weight management recommendations and prognostic factors for patients with this cancer.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals diagnosed with non-metastatic clear cell renal cell carcinoma who have undergone nephrectomy.

Not a fit: Patients with metastatic clear cell renal cell carcinoma or those who have not undergone nephrectomy may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved treatment strategies and personalized care for kidney cancer patients based on their body composition.

How similar studies have performed: Previous research has indicated that body composition can significantly impact cancer outcomes, suggesting that this approach may yield valuable insights.

Where this research is happening

New York, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-10 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.