Investigating blood vessel markers to predict kidney transplant success
Evaluation of Angiopoietins as Prognostic Markers of Kidney Allograft Structure and Function
This study is looking at how certain markers in your blood can help doctors understand how well your kidney transplant is working, which could lead to better care for kidney transplant patients like you.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Yale University NIH-funded |
| Lab location | 1 site (New Haven, United States) |
| Project ID | NIH-11098477 on NIH RePORTER |
What this research studies
This research focuses on understanding how specific markers in the blood, known as angiopoietins, can indicate the health and function of kidney transplants. By measuring the levels of Angiopoietin-1 and Angiopoietin-2, the study aims to assess blood vessel integrity in kidney transplant patients. The researchers will analyze blood samples and biopsy results to determine if these markers can help predict graft failure or complications. This could lead to better monitoring and management strategies for kidney transplant recipients.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals who have received a kidney transplant and are undergoing regular follow-up care.
Not a fit: Patients who have not undergone kidney transplantation or those with acute kidney injury unrelated to transplantation may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could improve the outcomes of kidney transplants by providing a reliable way to predict and prevent graft failure.
How similar studies have performed: Previous research has shown that monitoring vascular markers can be beneficial in predicting outcomes in transplant patients, suggesting a promising avenue for this study.
Where this research is happening
New Haven, United States
- Yale University — New Haven, United States (Active)
Researchers
- Principal investigator: Mansour, Sherry George — Yale University
- Study coordinator: Mansour, Sherry George
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.