Investigating blood pressure management in patients with left ventricular assist devices

Blood Pressure and Outcomes in Contemporary Left Ventricular Assist Device Recipients

['FUNDING_R01'] · UNIVERSITY OF PENNSYLVANIA · NIH-11099944

This study is looking at the best blood pressure levels for people with advanced heart failure who use special heart pumps, to help find the best ways to manage their blood pressure and improve their health.

Quick facts

Phase['FUNDING_R01']
Study typeNih_funding
SexAll
SponsorUNIVERSITY OF PENNSYLVANIA (nih funded)
Locations1 site (PHILADELPHIA, UNITED STATES)
Trial IDNIH-11099944 on ClinicalTrials.gov

What this research studies

This research focuses on understanding the optimal blood pressure (BP) range for patients who are supported by continuous-flow left ventricular assist devices (CF-LVADs). It aims to identify how different BP levels affect health outcomes, particularly in advanced heart failure patients. The study will analyze data from a large patient database to determine the best BP management strategies and medication regimens for these patients, especially considering factors like gender and race. By employing time-dependent analysis, the research seeks to provide more accurate insights into BP control and its implications for patient health.

Who could benefit from this research

Good fit: Ideal candidates for this research include advanced heart failure patients who are currently receiving support from continuous-flow left ventricular assist devices.

Not a fit: Patients who are not receiving left ventricular assist devices or those with conditions unrelated to blood pressure management may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved blood pressure management strategies that enhance the health outcomes of patients with left ventricular assist devices.

How similar studies have performed: Previous studies have indicated that blood pressure management is crucial for LVAD patients, but this research aims to provide novel insights specific to contemporary devices.

Where this research is happening

PHILADELPHIA, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.