Investigating blood flow issues in the eyes of patients with Sickle Cell Disease
SCD REVIVE - Retina to Evaluate Vaso occlusion In the Vasculature of the Eye
['FUNDING_R01'] · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · NIH-11061260
This study is looking at how Sickle Cell Disease affects blood flow in the eyes to find new ways to understand and track the disease better, which could help improve care for people living with SCD.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI (nih funded) |
| Locations | 1 site (NEW YORK, UNITED STATES) |
| Trial ID | NIH-11061260 on ClinicalTrials.gov |
What this research studies
This research focuses on Sickle Cell Disease (SCD), a serious blood disorder that leads to pain and organ damage. By using advanced imaging techniques, such as Optical Coherence Tomography Angiography (OCTA) and Adaptive Optics Scanning Light Ophthalmoscopy (AOSLO), the study aims to visualize and measure blood flow in the retina. This approach allows researchers to identify new biomarkers that can better predict the severity of SCD and improve disease monitoring. The goal is to enhance understanding of the disease mechanisms and ultimately improve patient outcomes.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with Sickle Cell Disease, particularly those experiencing complications related to blood flow.
Not a fit: Patients without Sickle Cell Disease or those with other unrelated eye conditions may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more accurate monitoring of Sickle Cell Disease and better management of its complications.
How similar studies have performed: Previous research has shown promise in using retinal imaging to assess vascular conditions, suggesting that this approach may yield valuable insights for Sickle Cell Disease.
Where this research is happening
NEW YORK, UNITED STATES
- ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI — NEW YORK, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: GLASSBERG, JEFFREY AVINS — ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI
- Study coordinator: GLASSBERG, JEFFREY AVINS
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.