Investigating blood flow development in children with single ventricle heart disease
Pulmonary Vascular Development in Single Ventricle Heart Disease: A Longitudinal Biomarker Approach
This study is looking at how heart surgery affects the growth of blood vessels in the lungs of children with single ventricle heart disease, by checking their blood and using special imaging to help understand what helps them do better or worse after surgery.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Colorado Denver NIH-funded |
| Lab location | 1 site (Aurora, UNITED STATES) |
| Project ID | NIH-11002340 on NIH RePORTER |
What this research studies
This research focuses on understanding how pulmonary vascular development is affected in children with single ventricle heart disease (SVHD). It aims to measure specific biomarkers in the blood before and after surgical procedures to see how these relate to the development of blood vessels in the lungs. By tracking these changes over time, the study hopes to identify factors that contribute to better or worse outcomes for these children. The approach includes using advanced imaging techniques and blood tests to gather comprehensive data on the patients' health.
Who could benefit from this research
Good fit: Ideal candidates for this research are children aged 0-11 years diagnosed with single ventricle heart disease.
Not a fit: Patients with heart conditions other than single ventricle heart disease may not receive any benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved diagnostic and treatment options for children with single ventricle heart disease, potentially enhancing their quality of life.
How similar studies have performed: Previous research has shown promising results in understanding pulmonary vascular development in similar patient populations, suggesting that this approach may yield valuable insights.
Where this research is happening
Aurora, UNITED STATES
- University of Colorado Denver — Aurora, United States (Active)
Researchers
- Principal investigator: Frank, Benjamin S — University of Colorado Denver
- Study coordinator: Frank, Benjamin S
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.