Investigating blood flow changes in Alzheimer's Disease
Cerebral hemodynamic impairment in symptomatic and asymptomatic Alzheimer's Disease
This study is looking at how blood flow in the brain changes in people with Alzheimer's Disease, both before they show symptoms and after, to help us understand how it relates to memory and thinking problems.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Emory University NIH-funded |
| Lab location | 1 site (Atlanta, United States) |
| Project ID | NIH-11014428 on NIH RePORTER |
What this research studies
This research focuses on understanding how blood flow in the brain is affected in individuals with Alzheimer's Disease (AD), both before and after symptoms appear. Using advanced MRI techniques, the study will measure cerebrovascular reactivity, which is a key indicator of vascular health, in different groups of participants, including healthy individuals and those with varying stages of AD. By examining these changes over time, the research aims to uncover the relationship between blood flow and cognitive decline in Alzheimer's patients.
Who could benefit from this research
Good fit: Ideal candidates for this research include adults aged 21 and older, particularly those who are cognitively normal but have positive biomarkers for Alzheimer's pathology, as well as those with mild cognitive impairment.
Not a fit: Patients with advanced Alzheimer's Disease who are already experiencing significant cognitive decline may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to earlier detection and better management strategies for Alzheimer's Disease.
How similar studies have performed: Previous research has shown promising results in understanding cerebrovascular function in Alzheimer's, indicating that this approach could yield valuable insights.
Where this research is happening
Atlanta, United States
- Emory University — Atlanta, United States (Active)
Researchers
- Principal investigator: Qiu, Deqiang — Emory University
- Study coordinator: Qiu, Deqiang
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.