Investigating blood DNA changes in COVID-19 survivors
Official title: Blood DNA Methylation Biomarkers of Post Acute Sequelae of SARS CoV 2 Infection (PASC)
Funded at Albany Medical College · NIH-10881924 · Data updated 2026-11-12
This study is looking at how COVID-19 might change the DNA in your blood and how those changes could affect your health later on, especially for people who are still feeling unwell after recovering from the virus.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Albany Medical College NIH-funded |
| Lab location | 1 site (Albany, United States) |
| Project start | July 5, 2023 |
| Project end | June 30, 2028 |
| Funding year | 2024 |
| Award (this year) | $778,634 |
| NIH project number | 5R01AI173035-02 |
| Project ID | NIH-10881924 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals who have recovered from COVID-19 and are experiencing ongoing health problems.
✕Less likely to help
Patients who have not been infected with COVID-19 or those who do not exhibit any post-acute sequelae may not benefit from this research.
What this research studies
This research focuses on understanding how COVID-19 affects blood DNA methylation, which may influence long-term health outcomes for survivors. By analyzing blood samples from patients, the study aims to identify specific DNA changes that occur during and after COVID-19 infection. The researchers will use advanced sequencing techniques to explore how these changes relate to ongoing health issues experienced by some individuals after recovering from the virus. This could help in understanding the lasting effects of COVID-19 and guide future treatments.
Why it matters
Potential benefit: If successful, this research could lead to better understanding and management of long-term health issues faced by COVID-19 survivors.
How similar studies have gone: Other research has shown promising results in understanding the long-term effects of viral infections through similar epigenetic approaches.
Where this research is happening
-
Albany Medical College
Albany, United States Active
Researchers
- Principal investigator: Jaitovich, Adolfo Ariel — Albany Medical College
- Study coordinator: Jaitovich, Adolfo Ariel
Related research
Other NIH-funded projects on the same topics.
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How COVID-19 infection and genes may influence memory and dementia risk
This study looks at how getting COVID-19 and a person’s genes together affect the chance of developing memory problems and Alzheimer’s disease later in life.
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Alzheimer’s-related dementia after COVID-19: how SARS-CoV-2 affects the brain and potential drug repurposing
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-
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Maternal SARS-CoV-2 infection and its effects on placenta and child development
This grant studies how COVID-19 infection during pregnancy might change the placenta and influence a child’s brain development, especially in kids who may be at higher genetic risk for ADHD/ASD.
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How COVID-19 and genetics influence memory and dementia risk in older adults
This project studies how getting COVID-19 interacts with people’s genetic makeup to affect the likelihood of cognitive decline and Alzheimer’s disease in older adults from diverse backgrounds.
-
Impact of COVID-19 on latent TB reactivation in Kenya
This project in Kenya checks how having had COVID-19 might influence the reactivation of latent tuberculosis in adults.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.