Investigating blood clotting risks in transgender youth starting hormone therapy
Thrombosis Risk in Transgender Adolescents and Young Adults Starting Gender-Affirming Hormone Therapy
This study is looking at how starting estrogen hormone therapy affects blood clotting in transgender teens and young adults, so we can better understand who might need extra precautions to stay safe while they transition.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Cincinnati Childrens Hosp Med Ctr NIH-funded |
| Lab location | 1 site (Cincinnati, United States) |
| Project ID | NIH-10876340 on NIH RePORTER |
What this research studies
This research focuses on transgender adolescents and young adults who are beginning gender-affirming hormone therapy (GAHT), particularly estrogen. It aims to understand how this therapy may affect blood clotting risks and to identify which individuals may need additional preventive measures against thrombosis. The study will involve monitoring biological changes in participants and gathering insights from healthcare providers about their practices and attitudes towards managing these risks. By addressing the current lack of guidelines, the research seeks to improve care for transgender youth undergoing GAHT.
Who could benefit from this research
Good fit: Ideal candidates for this research are transgender adolescents and young adults who are starting or considering gender-affirming hormone therapy.
Not a fit: Patients who are not undergoing hormone therapy or who are older than 21 years may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to better management strategies for preventing blood clots in transgender youth receiving hormone therapy.
How similar studies have performed: While there is limited research specifically on thrombosis risk in transgender youth undergoing GAHT, studies in related areas have shown the importance of understanding hormone therapy's effects on health outcomes.
Where this research is happening
Cincinnati, United States
- Cincinnati Childrens Hosp Med Ctr — Cincinnati, United States (Active)
Researchers
- Principal investigator: Mullins, Tanya L. Kowalczyk — Cincinnati Childrens Hosp Med Ctr
- Study coordinator: Mullins, Tanya L. Kowalczyk
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.