Investigating blood biomarkers and risk factors for Alzheimer's disease in men and women
Sex-specific risk factors and trajectories of blood biomarkers for Alzheimer's disease and related dementias
This study is looking at how different factors for men and women might affect the chances of developing Alzheimer's and related memory issues, using blood tests to spot those at higher risk before they show any symptoms, so we can help with early diagnosis and prevention.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Hennepin Healthcare Research Institute NIH-funded |
| Lab location | 1 site (Minneapolis, United States) |
| Project ID | NIH-11063450 on NIH RePORTER |
What this research studies
This research focuses on understanding how sex-specific factors influence the risk of developing Alzheimer's disease and related dementias (ADRD). By examining blood biomarkers associated with these conditions, the study aims to identify individuals at high risk before symptoms appear. The approach includes analyzing data from older adults in the community, considering various health factors and how they differ between men and women. The goal is to create a personalized risk score that can help in early diagnosis and prevention strategies.
Who could benefit from this research
Good fit: Ideal candidates for this research are older adults living in the community who are currently healthy and have no diagnosed dementia.
Not a fit: Patients who are already diagnosed with Alzheimer's disease or related dementias may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved early detection and personalized prevention strategies for Alzheimer's disease and related dementias.
How similar studies have performed: While there has been research on Alzheimer's risk factors, this study's focus on sex-specific biomarkers and community-based longitudinal analysis is relatively novel.
Where this research is happening
Minneapolis, United States
- Hennepin Healthcare Research Institute — Minneapolis, United States (Active)
Researchers
- Principal investigator: Murray, Anne M — Hennepin Healthcare Research Institute
- Study coordinator: Murray, Anne M
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.