Investigating biomarkers for lung cancer detection in patients with uncertain pulmonary nodules
The Boston University - UCLA Lung Cancer Biomarker Characterization Center
This study is looking for better ways to tell if certain lung nodules might be cancerous, using simple tests like analyzing gene patterns from nasal swabs, so patients with these nodules can avoid more invasive procedures.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Boston University Medical Campus NIH-funded |
| Lab location | 1 site (Boston, United States) |
| Project ID | NIH-10888980 on NIH RePORTER |
What this research studies
This research focuses on improving the detection of lung cancer in patients who have intermediate risk indeterminate pulmonary nodules (IPN). It aims to develop and validate minimally invasive biomarkers that can help classify these nodules as either low or high risk for malignancy, reducing the need for invasive tissue sampling. The study will utilize innovative approaches, including analyzing gene expression patterns from nasal swabs, to enhance diagnostic accuracy. By standardizing these biomarkers, the research seeks to transform the clinical management of patients with IPN.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals with intermediate risk indeterminate pulmonary nodules who require further evaluation for lung cancer.
Not a fit: Patients with clearly defined benign or malignant nodules may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more accurate and less invasive methods for diagnosing lung cancer, ultimately improving patient outcomes.
How similar studies have performed: Previous research has shown promise in using nasal biomarkers for lung cancer detection, indicating a potential for success in this innovative approach.
Where this research is happening
Boston, United States
- Boston University Medical Campus — Boston, United States (Active)
Researchers
- Principal investigator: Lenburg, Marc Elliott — Boston University Medical Campus
- Study coordinator: Lenburg, Marc Elliott
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.