Investigating biomarkers for diagnosing alcoholic acute pancreatitis
Biomarkers and pathogenesis of Alcoholic acute pancreatitis
['FUNDING_R01'] · MAYO CLINIC ARIZONA · NIH-11045636
This study is looking to find a better way to diagnose alcoholic acute pancreatitis by checking for specific fatty acids in the blood, which could help doctors tell how serious the condition is, even when other tests don’t work well.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | MAYO CLINIC ARIZONA (nih funded) |
| Locations | 1 site (SCOTTSDALE, UNITED STATES) |
| Trial ID | NIH-11045636 on ClinicalTrials.gov |
What this research studies
This research focuses on improving the diagnosis of alcoholic acute pancreatitis (AAP), a condition that affects many patients but is often misdiagnosed due to unreliable biomarkers. The study aims to validate fatty acids ethyl esters (FAEEs) as potential biomarkers that can indicate the presence and severity of AAP, even in cases where traditional alcohol detection fails. By analyzing blood samples for FAEEs, researchers hope to provide a more accurate diagnosis and better predict patient outcomes. The study will involve comparing FAEE levels in patients with AAP against those with other forms of acute pancreatitis.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals who have been diagnosed with acute pancreatitis, particularly those with a history of alcohol consumption.
Not a fit: Patients who do not have acute pancreatitis or those whose condition is unrelated to alcohol consumption may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more accurate diagnoses and improved treatment strategies for patients suffering from alcoholic acute pancreatitis.
How similar studies have performed: Previous research has shown promise in using biomarkers like FAEEs for diagnosing other alcohol-related conditions, suggesting potential success for this approach in AAP.
Where this research is happening
SCOTTSDALE, UNITED STATES
- MAYO CLINIC ARIZONA — SCOTTSDALE, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: SINGH, VIJAY PREM — MAYO CLINIC ARIZONA
- Study coordinator: SINGH, VIJAY PREM
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.