Investigating biomarkers for diagnosing alcoholic acute pancreatitis
Official title: Biomarkers and pathogenesis of Alcoholic acute pancreatitis
Funded at Mayo Clinic Arizona · NIH-11045636 · Data updated 2026-11-12
This study is looking to find a better way to diagnose alcoholic acute pancreatitis by checking for specific fatty acids in the blood, which could help doctors tell how serious the condition is, even when other tests don’t work well.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Mayo Clinic Arizona NIH-funded |
| Lab location | 1 site (Scottsdale, United States) |
| Project start | March 1, 2024 |
| Project end | November 30, 2028 |
| Funding year | 2025 |
| Award (this year) | $517,938 |
| NIH project number | 5R01AA031257-02 |
| Project ID | NIH-11045636 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals who have been diagnosed with acute pancreatitis, particularly those with a history of alcohol consumption.
✕Less likely to help
Patients who do not have acute pancreatitis or those whose condition is unrelated to alcohol consumption may not benefit from this research.
What this research studies
This research focuses on improving the diagnosis of alcoholic acute pancreatitis (AAP), a condition that affects many patients but is often misdiagnosed due to unreliable biomarkers. The study aims to validate fatty acids ethyl esters (FAEEs) as potential biomarkers that can indicate the presence and severity of AAP, even in cases where traditional alcohol detection fails. By analyzing blood samples for FAEEs, researchers hope to provide a more accurate diagnosis and better predict patient outcomes. The study will involve comparing FAEE levels in patients with AAP against those with other forms of acute pancreatitis.
Why it matters
Potential benefit: If successful, this research could lead to more accurate diagnoses and improved treatment strategies for patients suffering from alcoholic acute pancreatitis.
How similar studies have gone: Previous research has shown promise in using biomarkers like FAEEs for diagnosing other alcohol-related conditions, suggesting potential success for this approach in AAP.
Where this research is happening
-
Mayo Clinic Arizona
Scottsdale, United States Active
Researchers
- Principal investigator: Singh, Vijay Prem — Mayo Clinic Arizona
- Study coordinator: Singh, Vijay Prem
Related research
Other NIH-funded projects on the same topics.
-
Diabetes after acute pancreatitis: understanding and tracking progression
A patient-focused look at how diabetes can develop after an episode of acute pancreatitis, using data from a large, ongoing study and AI insights.
-
Continuation of Type 1 Diabetes in Acute Pancreatitis: UF Health and AdventHealth
A patient-facing overview of a long-term study tracking people with acute pancreatitis to understand how some develop type 1 diabetes later and what factors influence that process.
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Data Coordinating Center for Type 1 Diabetes in Acute Pancreatitis Consortium
A national effort to learn how pancreatitis-related Type 1 diabetes develops, by tracking patients and coordinating data to improve future care.
-
Diabetes after acute pancreatitis: a patient-focused network study
A program at Indiana University is studying how diabetes can develop after an acute pancreatitis episode, with new findings that could help doctors tailor care for adults who had pancreatitis.
-
Type 1 Diabetes in Acute Pancreatitis in Diabetes Patients at Stanford
A Stanford-led project helps people with brittle type 1 diabetes who also experience pancreatitis by following them in a long-term study to understand how acute pancreatitis affects diabetes.
-
Epidemiology and causes of diabetes after acute pancreatitis
A long-term study following people who have had acute pancreatitis to understand how often diabetes develops, why it happens, and how it progresses.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.