Investigating biomarkers for chronic obstructive pulmonary disease (COPD)
Patient oriented research and mentoring in COPD biomarker studies
['FUNDING_OTHER'] · BRIGHAM AND WOMEN'S HOSPITAL · NIH-11051504
This study is looking for special markers in the blood and lung fluid of people with COPD to better understand how the disease changes over time and how well treatments work, all while helping doctors learn more about this important research.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | BRIGHAM AND WOMEN'S HOSPITAL (nih funded) |
| Locations | 1 site (BOSTON, UNITED STATES) |
| Trial ID | NIH-11051504 on ClinicalTrials.gov |
What this research studies
This research focuses on chronic obstructive pulmonary disease (COPD), a complex condition that varies significantly among patients. It aims to identify specific biomarkers that can indicate disease progression, acute exacerbations, and responses to treatment, thereby enhancing personalized medicine approaches. The study will involve collecting blood and bronchoalveolar lavage fluid samples from patients undergoing bronchoscopy procedures, and will utilize advanced techniques like RNA-sequencing to analyze these samples. Additionally, the project emphasizes training physician-scientists in the necessary skills for conducting large-scale genetic epidemiology studies.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with chronic obstructive pulmonary disease (COPD), particularly those experiencing frequent exacerbations or rapid declines in lung function.
Not a fit: Patients with stable COPD who do not experience exacerbations or those with other unrelated respiratory conditions may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more precise and effective treatments for COPD patients based on their unique disease characteristics.
How similar studies have performed: Previous research has shown promise in identifying biomarkers for COPD, suggesting that this approach could yield valuable insights and advancements in treatment.
Where this research is happening
BOSTON, UNITED STATES
- BRIGHAM AND WOMEN'S HOSPITAL — BOSTON, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: HERSH, CRAIG P — BRIGHAM AND WOMEN'S HOSPITAL
- Study coordinator: HERSH, CRAIG P
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Airway Disease, atherosclerotic coronary disease