Investigating biomarkers for Alzheimer's disease in diverse populations
HABS-HD - Core D - Omics Core
This study is looking for special markers in blood and spinal fluid that can help us understand Alzheimer's disease better, especially in African Americans, Mexican Americans, and non-Hispanic whites, so we can improve how we diagnose and treat the condition, and you can help by sharing your samples!
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of North Texas Hlth Sci Ctr NIH-funded |
| Lab location | 1 site (Fort Worth, United States) |
| Project ID | NIH-10916337 on NIH RePORTER |
What this research studies
This research focuses on identifying sensitive biomarkers for Alzheimer's disease (AD) using biofluids like blood and cerebrospinal fluid (CSF). It aims to conduct a large-scale, systematic study that combines multi-level 'omics' approaches with established biomarkers among African Americans, Mexican Americans, and non-Hispanic whites. By analyzing these biomarkers, the research seeks to uncover population-specific pathways related to cognitive decline and improve diagnosis and treatment strategies for AD. Patients may have their samples collected and analyzed to contribute to this important work.
Who could benefit from this research
Good fit: Ideal candidates for participation include individuals from African American, Mexican American, and non-Hispanic white backgrounds who are experiencing cognitive decline or have been diagnosed with mild cognitive impairment or Alzheimer's disease.
Not a fit: Patients who do not belong to the targeted racial/ethnic groups or those without cognitive decline may not receive benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more accurate and tailored diagnostic and treatment options for Alzheimer's disease in diverse populations.
How similar studies have performed: Previous research has shown success in identifying biomarkers for Alzheimer's disease, but this study is novel in its focus on diverse populations and multi-level omics approaches.
Where this research is happening
Fort Worth, United States
- University of North Texas Hlth Sci Ctr — Fort Worth, United States (Active)
Researchers
- Principal investigator: Johnson, Leigh a — University of North Texas Hlth Sci Ctr
- Study coordinator: Johnson, Leigh a
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.