Investigating biomarkers and biosamples related to Alzheimer's disease and related dementias
Core C - Human Consultation-Biosamples-Biomarkers Core
This study is looking at how Alzheimer's disease and similar conditions work in people by analyzing samples from patients, so we can better understand the disease and make sure our findings from animal studies apply to humans.
Quick facts
| Grant type | P01 program project |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Kentucky NIH-funded |
| Lab location | 1 site (Lexington, United States) |
| Project ID | NIH-10897074 on NIH RePORTER |
What this research studies
This research focuses on understanding the complex biology of Alzheimer's disease and related dementias by analyzing human biosamples and biomarkers. It aims to validate findings from mouse models in human subjects, ensuring that the results are clinically relevant. The project will optimize study designs and manage data streams that include molecular and metabolic information from human cases. By examining a set of 100 cases, the research will assess various biochemical and neuropathological endpoints to enhance our understanding of these conditions.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals diagnosed with Alzheimer's disease or related dementias, as well as healthy controls for comparison.
Not a fit: Patients with other unrelated neurological conditions may not receive benefits from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved diagnostic tools and treatment strategies for Alzheimer's disease and related dementias.
How similar studies have performed: Previous research has shown success in using similar approaches to study Alzheimer's disease, indicating a promising avenue for further exploration.
Where this research is happening
Lexington, United States
- University of Kentucky — Lexington, United States (Active)
Researchers
- Principal investigator: Nelson, Peter T. — University of Kentucky
- Study coordinator: Nelson, Peter T.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.