Investigating biological factors that may lead to alcohol use disorders in young adults with bipolar disorder.

Biological Risk Factors for the Prospective Development of Alcohol Use Disorders in Young Adults with Bipolar Disorder and Typically Developing Young Adults

NIH-funded research University of Texas at Austin · NIH-11026442

This study is looking at how certain biological factors and life experiences might lead to alcohol problems in young adults with bipolar disorder, using brain scans to see how things change over time, so we can find better ways to help those who are affected.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of Texas at Austin NIH-funded
Lab location1 site (Austin, United States)
Project IDNIH-11026442 on NIH RePORTER

What this research studies

This research focuses on understanding how biological risk factors contribute to the development of alcohol use disorders (AUDs) in young adults, particularly those with bipolar disorder. By using advanced neuroimaging techniques, the study aims to track changes in brain structure and function over time, while also examining how stress and early life experiences may influence alcohol responses. Participants will be monitored through a longitudinal approach to identify predictors of AUDs and improve prevention strategies. The goal is to clarify the mechanisms behind this comorbidity to enhance treatment outcomes for affected individuals.

Who could benefit from this research

Good fit: Ideal candidates for this research are young adults aged 12 to 20 who have been diagnosed with bipolar disorder or are typically developing individuals in the same age range.

Not a fit: Patients who are outside the age range of 12 to 20 or do not have a diagnosis of bipolar disorder may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to better prevention and intervention strategies for alcohol use disorders in young adults with bipolar disorder.

How similar studies have performed: While there has been limited longitudinal research on this specific topic, previous studies have shown promising results in understanding the relationship between alcohol use and bipolar disorder.

Where this research is happening

Austin, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.