Investigating balance issues in older adults with Parkinson's disease
Central cholinergic presbyvestibulopathy network changes and imbalance in Parkinson's disease and older persons
['FUNDING_R01'] · UNIVERSITY OF MICHIGAN AT ANN ARBOR · NIH-11084460
This study is looking at how changes in the brain's communication system can affect balance and movement in older adults with Parkinson's disease, and it aims to find ways to help improve these challenges.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF MICHIGAN AT ANN ARBOR (nih funded) |
| Locations | 1 site (ANN ARBOR, UNITED STATES) |
| Trial ID | NIH-11084460 on ClinicalTrials.gov |
What this research studies
This research focuses on understanding how changes in the cholinergic system affect balance and mobility in older adults, particularly those with Parkinson's disease. It aims to identify the relationship between vestibular dysfunction, cognitive decline, and postural instability, which are common challenges faced by this population. By utilizing advanced imaging techniques, the study will explore brain regions involved in balance and sensory processing to uncover potential therapeutic targets. Patients may undergo assessments to evaluate their balance and cognitive function as part of the research.
Who could benefit from this research
Good fit: Ideal candidates for this research include older adults aged 65 and above who are diagnosed with Parkinson's disease and experience balance difficulties.
Not a fit: Patients who are younger than 65 or do not have Parkinson's disease may not receive benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved strategies for managing balance and mobility issues in older adults with Parkinson's disease, enhancing their quality of life.
How similar studies have performed: Previous research has shown promising results in understanding the role of vestibular dysfunction in balance issues among older adults, suggesting that this approach may yield valuable insights.
Where this research is happening
ANN ARBOR, UNITED STATES
- UNIVERSITY OF MICHIGAN AT ANN ARBOR — ANN ARBOR, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: BOHNEN, NICOLAAS IDA — UNIVERSITY OF MICHIGAN AT ANN ARBOR
- Study coordinator: BOHNEN, NICOLAAS IDA
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.