Investigating arterial stiffness in mothers and infants to prevent heart disease
Official title: Arterial stiffness in mother/infant dyads: Life course approach to prevent cardiovascular disease
Funded at Univ of North Carolina Chapel Hill · NIH-11170270 · Data updated 2026-11-12
This study is looking at how the stiffness of blood vessels affects the heart health of pregnant women and their babies, and it aims to find ways to lower the risk of heart disease for both moms and kids over three years after childbirth.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Univ of North Carolina Chapel Hill NIH-funded |
| Lab location | 1 site (Chapel Hill, United States) |
| Project start | August 1, 2021 |
| Project end | July 31, 2025 |
| Funding year | 2024 |
| Award (this year) | $192,755 |
| NIH project number | 3R01HL157075-04S2 |
| Project ID | NIH-11170270 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include pregnant women, particularly those who are healthy or have medical complications during pregnancy.
✕Less likely to help
Patients who are not pregnant or who do not have a connection to maternal or infant health may not benefit from this research.
What this research studies
This research focuses on understanding how arterial stiffness, a key indicator of cardiovascular health, affects both mothers and their infants during and after pregnancy. By enrolling 840 pregnant women, the study aims to measure central pulse wave velocity, which helps predict cardiovascular disease risk. The research will also explore how various personal and social factors influence cardiovascular health over a three-year period postpartum. This approach seeks to identify effective strategies to reduce heart disease risk in women and their children.
Why it matters
Potential benefit: If successful, this research could lead to improved prevention strategies for cardiovascular disease in women and their children.
How similar studies have gone: Other research has shown success in using similar approaches to assess cardiovascular risk in pregnant women, indicating a promising avenue for this study.
Where this research is happening
-
Univ of North Carolina Chapel Hill
Chapel Hill, United States Active
Researchers
- Principal investigator: Meyer, Michelle — Univ of North Carolina Chapel Hill
- Study coordinator: Meyer, Michelle
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Investigating arterial stiffness in mothers and infants to prevent heart disease
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-
Investigating arterial stiffness in mothers and infants to prevent heart disease
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.