NIH-funded research R01 grant

Investigating arterial stiffness in mothers and infants to prevent heart disease

Official title: Arterial stiffness in mother/infant dyads: Life course approach to prevent cardiovascular disease

Funded at Univ of North Carolina Chapel Hill · NIH-11170261 · Data updated 2026-11-12

This study is looking at how stiff arteries can impact the heart health of moms and their babies during and after pregnancy, especially for non-Hispanic Black and Latina women, to help create better care practices that keep both mothers and their children healthy.

More Cardiovascular Disease research and trials

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniv of North Carolina Chapel Hill
NIH-funded
Lab location1 site (Chapel Hill, United States)
Project startAugust 1, 2021
Project endJuly 31, 2025
Funding year2024
Award (this year)$176,657
NIH project number3R01HL157075-04S1
Project IDNIH-11170261 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research include pregnant women, particularly those who are healthy or have medical complications, and their infants.

Less likely to help

Patients who are not pregnant or who do not have a connection to maternal health may not benefit from this research.

What this research studies

This research focuses on understanding how arterial stiffness affects both mothers and their infants, particularly during and after pregnancy. By measuring central pulse wave velocity, a key indicator of vascular health, the study aims to identify cardiovascular disease (CVD) risks that are often overlooked in women, especially among non-Hispanic Black and Latina populations. The research will involve a cohort of 840 pregnant women and their infants, tracking health outcomes for three years postpartum. The goal is to develop effective care practices that can reduce CVD risk for both mothers and their children.

Why it matters

Potential benefit: If successful, this research could lead to improved strategies for preventing cardiovascular disease in women and their children.

How similar studies have gone: Previous research has shown that early detection of cardiovascular risks during pregnancy can lead to better health outcomes, indicating that this approach has potential for success.

Where this research is happening

  • Univ of North Carolina Chapel Hill
    Chapel Hill, United States
    Active

Researchers

  • Principal investigator: Meyer, Michelle — Univ of North Carolina Chapel Hill
  • Study coordinator: Meyer, Michelle

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.