NIH-funded research R01 grant

Investigating arterial stiffness in mothers and infants to prevent heart disease

Official title: Arterial stiffness in mother/infant dyads: Life course approach to prevent cardiovascular disease

Funded at Univ of North Carolina Chapel Hill · NIH-10908540 · Data updated 2026-11-12

This study is looking at how the stiffness of blood vessels in pregnant women and their babies can help us understand the risk of heart problems later on, especially for non-Hispanic Black and Latina families, so we can find better ways to keep both moms and their kids healthy.

More Cardiovascular Disease research and trials

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniv of North Carolina Chapel Hill
NIH-funded
Lab location1 site (Chapel Hill, United States)
Project startAugust 1, 2021
Project endJuly 31, 2025
Funding year2024
Award (this year)$668,109
NIH project number5R01HL157075-04
Project IDNIH-10908540 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research include pregnant women, particularly those who are healthy or have medical complications, and their infants.

Less likely to help

Patients who are not pregnant or do not have children may not receive any benefit from this research.

What this research studies

This research focuses on understanding how arterial stiffness in mothers and their infants can indicate the risk of cardiovascular disease (CVD). By examining pregnant women and their children, the study aims to identify risk factors that contribute to CVD, particularly in non-Hispanic Black and Latina populations who are at higher risk. The research will involve measuring central pulse wave velocity, a key indicator of vascular health, and will track participants for three years postpartum to assess ongoing risk. The goal is to develop better healthcare practices that can reduce CVD risk for both mothers and their children.

Why it matters

Potential benefit: If successful, this research could lead to improved prevention strategies for cardiovascular disease in women and their children.

How similar studies have gone: Other research has shown success in identifying cardiovascular risks during pregnancy, making this approach promising for further advancements.

Where this research is happening

  • Univ of North Carolina Chapel Hill
    Chapel Hill, United States
    Active

Researchers

  • Principal investigator: Meyer, Michelle — Univ of North Carolina Chapel Hill
  • Study coordinator: Meyer, Michelle

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.