Investigating antibiotic use in children with diarrhea in China and its link to antibiotic resistance
Official title: Understanding the Drivers of Antibiotic use in the Treatment of Childhood Diarrhea and Relationship to Antibiotic Resistance in China
Funded at Univ of North Carolina Chapel Hill · NIH-10897223 · Data updated 2026-11-12
This study looks at how and why doctors and parents in China give antibiotics to kids under 11 with diarrhea, even when they might not need them, to help find better ways to use these medicines wisely and keep them effective for everyone.
Quick facts
| Grant type | Career grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Univ of North Carolina Chapel Hill NIH-funded |
| Lab location | 1 site (Chapel Hill, United States) |
| Project start | August 22, 2022 |
| Project end | July 31, 2026 |
| Funding year | 2024 |
| Award (this year) | $124,335 |
| NIH project number | 5K01AI159233-03 |
| Project ID | NIH-10897223 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are children under 11 years old in China who are experiencing diarrhea.
✕Less likely to help
Patients who are not experiencing diarrhea or are older than 11 years may not benefit from this research.
What this research studies
This research examines how and why antibiotics are used to treat childhood diarrhea in China, particularly focusing on children under 11 years old. It aims to identify the factors that lead caregivers and healthcare providers to prescribe antibiotics, even when they may not be necessary. By understanding these drivers, the research seeks to inform better policies and interventions that can reduce unnecessary antibiotic use and combat antibiotic resistance. The study will involve analyzing data and conducting interviews to gather insights from caregivers and healthcare professionals.
Why it matters
Potential benefit: If successful, this research could lead to improved treatment practices for childhood diarrhea, reducing unnecessary antibiotic use and the associated risks of antibiotic resistance.
How similar studies have gone: Previous research has shown that addressing the drivers of antibiotic overuse can lead to significant improvements in antibiotic prescribing practices.
Where this research is happening
-
Univ of North Carolina Chapel Hill
Chapel Hill, United States Active
Researchers
- Principal investigator: Sylvia, Sean Y — Univ of North Carolina Chapel Hill
- Study coordinator: Sylvia, Sean Y
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.