Investigating antibiotic resistance in gonorrhea from the throat
Exploration of the oropharyngeal resistome as a reservoir of antimicrobial resistance in Neisseria gonorrhoeae
This study is looking at how some strains of gonorrhea bacteria that don't respond to antibiotics are found in the throat, especially in men who have sex with men, to help find better ways to treat and prevent the infection.
Quick facts
| Grant type | R21 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Washington NIH-funded |
| Lab location | 1 site (Seattle, United States) |
| Project ID | NIH-10657789 on NIH RePORTER |
What this research studies
This research focuses on understanding how antibiotic-resistant strains of Neisseria gonorrhoeae, the bacteria that causes gonorrhea, are present in the oropharynx, particularly among men who have sex with men (MSM). The study will utilize advanced techniques to identify both the bacteria and their resistance profiles, aiming to uncover the genetic factors contributing to antibiotic resistance. By analyzing samples from the throat, researchers hope to gain insights into the microbiota and the genetic makeup that allows these bacteria to survive despite treatment efforts. This comprehensive approach could lead to better strategies for managing and preventing gonorrhea infections.
Who could benefit from this research
Good fit: Ideal candidates for this research are men who have sex with men, particularly those diagnosed with or at high risk for gonorrhea.
Not a fit: Patients who do not have gonorrhea or are not part of the MSM community may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved treatment options and strategies for preventing antibiotic-resistant gonorrhea.
How similar studies have performed: Previous research has shown success in identifying antibiotic resistance patterns in other bacterial infections, suggesting that this approach may yield valuable insights.
Where this research is happening
Seattle, United States
- University of Washington — Seattle, United States (Active)
Researchers
- Principal investigator: Soge, Olusegun Olasunkanmi — University of Washington
- Study coordinator: Soge, Olusegun Olasunkanmi
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.