Investigating aging-related biomarkers in long-term survivors of Hodgkin lymphoma

Aging-Related Biomarkers of Neurocognitive Function in Long-term Hodgkin Lymphoma Survivors

NIH-funded research University of Rochester · NIH-10876288

This study is looking at how aging affects brain health in long-term survivors of Hodgkin lymphoma who didn't receive certain brain-targeting treatments, with the hope of finding clues that could help improve their memory and thinking skills.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionUniversity of Rochester NIH-funded
Lab location1 site (Rochester, United States)
Project IDNIH-10876288 on NIH RePORTER

What this research studies

This research focuses on understanding how aging-related biological factors contribute to neurocognitive impairment in long-term survivors of Hodgkin lymphoma who were not treated with therapies targeting the central nervous system. By analyzing existing data and biological samples from these survivors and community controls, the study aims to identify specific biomarkers linked to cognitive decline. The goal is to uncover the underlying mechanisms of neurocognitive issues in this population, which could lead to better prevention and intervention strategies.

Who could benefit from this research

Good fit: Ideal candidates for this research are long-term survivors of Hodgkin lymphoma who were treated without central nervous system-directed therapies.

Not a fit: Patients who have not survived Hodgkin lymphoma or those who received CNS-directed therapies may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved strategies for preventing cognitive decline in Hodgkin lymphoma survivors.

How similar studies have performed: Other research has indicated that examining biomarkers related to aging and cognitive function can yield valuable insights, suggesting this approach has potential for success.

Where this research is happening

Rochester, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-10 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.