Investigating aging-related biomarkers in long-term survivors of Hodgkin lymphoma
Official title: Aging-Related Biomarkers of Neurocognitive Function in Long-term Hodgkin Lymphoma Survivors
Funded at University of Rochester · NIH-10876288 · Data updated 2026-11-12
This study is looking at how aging affects brain health in long-term survivors of Hodgkin lymphoma who didn't receive certain brain-targeting treatments, with the hope of finding clues that could help improve their memory and thinking skills.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Rochester NIH-funded |
| Lab location | 1 site (Rochester, United States) |
| Project start | January 3, 2021 |
| Project end | June 30, 2026 |
| Funding year | 2024 |
| Award (this year) | $249,000 |
| NIH project number | 5R00CA256356-05 |
| Project ID | NIH-10876288 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are long-term survivors of Hodgkin lymphoma who were treated without central nervous system-directed therapies.
✕Less likely to help
Patients who have not survived Hodgkin lymphoma or those who received CNS-directed therapies may not benefit from this research.
What this research studies
This research focuses on understanding how aging-related biological factors contribute to neurocognitive impairment in long-term survivors of Hodgkin lymphoma who were not treated with therapies targeting the central nervous system. By analyzing existing data and biological samples from these survivors and community controls, the study aims to identify specific biomarkers linked to cognitive decline. The goal is to uncover the underlying mechanisms of neurocognitive issues in this population, which could lead to better prevention and intervention strategies.
Why it matters
Potential benefit: If successful, this research could lead to improved strategies for preventing cognitive decline in Hodgkin lymphoma survivors.
How similar studies have gone: Other research has indicated that examining biomarkers related to aging and cognitive function can yield valuable insights, suggesting this approach has potential for success.
Where this research is happening
-
University of Rochester
Rochester, United States Active
Researchers
- Principal investigator: Williams, Annalynn — University of Rochester
- Study coordinator: Williams, Annalynn
Related research
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.