Investigating aging and Alzheimer's disease using marmosets
Veterinary and Colony Management Core
['FUNDING_OTHER'] · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · NIH-10899740
This study is looking at small monkeys called common marmosets to learn more about aging and diseases like Alzheimer's, so we can find better ways to help people with these conditions.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF PITTSBURGH AT PITTSBURGH (nih funded) |
| Locations | 1 site (PITTSBURGH, UNITED STATES) |
| Trial ID | NIH-10899740 on ClinicalTrials.gov |
What this research studies
This research focuses on the common marmoset, a small primate that serves as a valuable model for studying aging and age-related diseases, particularly Alzheimer's disease and related dementias. The project utilizes these animals due to their short lifespan, allowing researchers to conduct longitudinal studies on the same individuals over time. Marmosets exhibit age-related changes similar to those seen in humans, including cognitive decline and the accumulation of beta-Amyloid, which are critical for understanding Alzheimer's disease progression. By studying these primates, researchers aim to gain insights that could lead to better treatments and interventions for Alzheimer's disease.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals experiencing early signs of Alzheimer's disease or related dementias.
Not a fit: Patients with advanced Alzheimer's disease or those not exhibiting any cognitive decline may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved understanding and treatment options for Alzheimer's disease and related dementias.
How similar studies have performed: Previous research using non-human primates has shown promise in understanding Alzheimer's disease, indicating that this approach could yield valuable insights.
Where this research is happening
PITTSBURGH, UNITED STATES
- UNIVERSITY OF PITTSBURGH AT PITTSBURGH — PITTSBURGH, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: STRICK, PETER — UNIVERSITY OF PITTSBURGH AT PITTSBURGH
- Study coordinator: STRICK, PETER
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Alzheimer disease dementia, Alzheimer syndrome, Alzheimer's Disease