Investigating age-related changes in skeletal health using animal models.
In Vivo Model and Histology Core
This study is looking into how aging affects bone health using animal models to help find better treatments for age-related bone diseases, and it's designed for anyone interested in improving care for these conditions.
Quick facts
| Grant type | P01 program project |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Johns Hopkins University NIH-funded |
| Lab location | 1 site (Baltimore, United States) |
| Project ID | NIH-11004725 on NIH RePORTER |
What this research studies
This research focuses on understanding the mechanisms behind age-related skeletal degenerative diseases through the use of animal models and histological analysis. A centralized facility will be established to conduct standardized procedures, ensuring high-quality and unbiased results. The core will employ skilled personnel to perform complex microsurgeries and histological grading, which will help in assessing the impact of aging on skeletal health. By utilizing various experimental techniques, the research aims to uncover insights that could lead to better treatments for age-related conditions.
Who could benefit from this research
Good fit: Ideal candidates for this research are older adults experiencing symptoms of skeletal degeneration or related conditions.
Not a fit: Patients who are not experiencing age-related skeletal issues or those with acute injuries unrelated to aging may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved understanding and treatment options for patients suffering from age-related skeletal diseases.
How similar studies have performed: Previous research has shown success in using animal models to study age-related diseases, indicating that this approach is both valid and valuable.
Where this research is happening
Baltimore, United States
- Johns Hopkins University — Baltimore, United States (Active)
Researchers
- Principal investigator: Zhen, Gehua — Johns Hopkins University
- Study coordinator: Zhen, Gehua
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.