Investigating acute kidney injury in patients with chronic kidney disease

Acute kidney injury among patients with chronic kidney disease

NIH-funded research University of California, San Francisco · NIH-10214596

This study is looking at how sudden kidney problems (AKI) impact people who already have long-term kidney issues (CKD), and it’s for patients in the Chronic Renal Insufficiency Cohort (CRIC) who want to understand how these episodes might affect their kidney health over time.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of California, San Francisco NIH-funded
Lab location1 site (San Francisco, United States)
Project IDNIH-10214596 on NIH RePORTER

What this research studies

This research focuses on understanding how acute kidney injury (AKI) affects individuals with chronic kidney disease (CKD). By analyzing hospital records from a large cohort study, researchers aim to identify episodes of AKI, assess their severity, and examine their long-term effects on kidney function. Patients enrolled in the Chronic Renal Insufficiency Cohort (CRIC) will have their data and biospecimens collected before and after AKI episodes to provide insights into the progression of CKD. This comprehensive approach seeks to clarify the relationship between AKI and CKD outcomes.

Who could benefit from this research

Good fit: Ideal candidates for this research are adults aged 21 and older who have been diagnosed with chronic kidney disease.

Not a fit: Patients without chronic kidney disease or those who are not experiencing acute kidney injury may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved management strategies for patients with chronic kidney disease, potentially slowing the progression of kidney damage.

How similar studies have performed: Previous research has shown that understanding the relationship between acute kidney injury and chronic kidney disease can lead to significant advancements in patient care.

Where this research is happening

San Francisco, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Cardiovascular Diseasescardiovascular disorder
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.