Investigating abaloparatide's role in healing bone fractures
BCCMA:Foundational Research to Act Upon and Resist Conditions unfavorable to bone (FRACTURECURB):Role of abaloparatide for fracture healing
This study is looking at how a medication called abaloparatide can help bones heal faster after fractures, especially for veterans who might take longer to recover, with the hope of finding better treatments to speed up healing.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Veterans Affairs Med Ctr San Francisco NIH-funded |
| Lab location | 1 site (San Francisco, United States) |
| Project ID | NIH-10950344 on NIH RePORTER |
What this research studies
This research focuses on understanding how abaloparatide, a medication similar to parathyroid hormone, can enhance the healing process of bone fractures. By using advanced laboratory models that mimic conditions affecting bone health, the team aims to identify mechanisms that can be targeted for improved fracture repair. The study will explore the biological processes involved in bone formation and repair, particularly in veterans who often experience delayed healing. The goal is to develop effective treatments that can significantly reduce recovery time for patients with fractures.
Who could benefit from this research
Good fit: Ideal candidates for this research include veterans and individuals with conditions that impair bone healing or increase fracture risk.
Not a fit: Patients with stable fractures that heal normally without complications may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to faster and more effective healing of bone fractures, particularly for patients with delayed healing.
How similar studies have performed: Previous research has shown promise in using parathyroid hormone treatments for fracture healing, suggesting that this approach may yield beneficial results.
Where this research is happening
San Francisco, United States
- Veterans Affairs Med Ctr San Francisco — San Francisco, United States (Active)
Researchers
- Principal investigator: Bikle, Daniel David — Veterans Affairs Med Ctr San Francisco
- Study coordinator: Bikle, Daniel David
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.