Investigating abaloparatide's role in healing bone fractures
Official title: BCCMA:Foundational Research to Act Upon and Resist Conditions unfavorable to bone (FRACTURECURB):Role of abaloparatide for fracture healing
Funded at Veterans Affairs Med Ctr San Francisco · NIH-10950344 · Data updated 2026-11-12
This study is looking at how a medication called abaloparatide can help bones heal faster after fractures, especially for veterans who might take longer to recover, with the hope of finding better treatments to speed up healing.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Veterans Affairs Med Ctr San Francisco NIH-funded |
| Lab location | 1 site (San Francisco, United States) |
| Project start | October 1, 2022 |
| Project end | September 30, 2026 |
| Funding year | 2025 |
| NIH project number | 5I01BX005854-03 |
| Project ID | NIH-10950344 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include veterans and individuals with conditions that impair bone healing or increase fracture risk.
✕Less likely to help
Patients with stable fractures that heal normally without complications may not benefit from this research.
What this research studies
This research focuses on understanding how abaloparatide, a medication similar to parathyroid hormone, can enhance the healing process of bone fractures. By using advanced laboratory models that mimic conditions affecting bone health, the team aims to identify mechanisms that can be targeted for improved fracture repair. The study will explore the biological processes involved in bone formation and repair, particularly in veterans who often experience delayed healing. The goal is to develop effective treatments that can significantly reduce recovery time for patients with fractures.
Why it matters
Potential benefit: If successful, this research could lead to faster and more effective healing of bone fractures, particularly for patients with delayed healing.
How similar studies have gone: Previous research has shown promise in using parathyroid hormone treatments for fracture healing, suggesting that this approach may yield beneficial results.
Where this research is happening
-
Veterans Affairs Med Ctr San Francisco
San Francisco, United States Active
Researchers
- Principal investigator: Bikle, Daniel David — Veterans Affairs Med Ctr San Francisco
- Study coordinator: Bikle, Daniel David
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.