Investigating a universal vaccine for influenza

NIAID Centers of Excellence for Influenza Research and Response: Universal Influenza Vaccine Research Activities

NIH-funded research University of Pennsylvania · NIH-11065380

This study is looking at how flu viruses change and spread, and how our immune system responds to them, so we can find better ways to protect people from the flu and create a vaccine that works for everyone for a longer time.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionUniversity of Pennsylvania NIH-funded
Lab location1 site (Philadelphia, United States)
Project IDNIH-11065380 on NIH RePORTER

What this research studies

This research focuses on understanding the factors that influence the evolution and transmission of influenza viruses, as well as the immune response to these infections. By conducting cohort studies and sampling from both humans and animals, the research aims to identify key immunological factors that can enhance protection against influenza. The goal is to improve vaccination strategies and develop a universal influenza vaccine that provides broader and longer-lasting immunity.

Who could benefit from this research

Good fit: Ideal candidates for participation include individuals who are at risk of influenza infection, such as those with underlying health conditions or those in close contact with high-risk populations.

Not a fit: Patients who are not at risk for influenza or those who have already received effective vaccination may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to the development of a universal influenza vaccine that offers better protection against various strains of the virus.

How similar studies have performed: Previous research has shown promise in developing universal vaccines for influenza, indicating that this approach has potential for success.

Where this research is happening

Philadelphia, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.