Investigating a treatment approach for men with low-grade prostate cancer under active surveillance
Phase II Clinical trial of GTC in Men on Active Surveillance
This study is for men with low-grade prostate cancer who are being watched closely instead of treated right away, and it’s testing whether a certain medication can help keep their cancer from getting worse while also helping them feel more confident and less anxious about their health decisions.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | H. Lee Moffitt Cancer Ctr & Res Inst NIH-funded |
| Lab location | 1 site (Tampa, United States) |
| Project ID | NIH-10853063 on NIH RePORTER |
What this research studies
This research focuses on men diagnosed with low-grade prostate cancer who are on active surveillance, a strategy that involves closely monitoring the disease rather than immediate treatment. The study aims to evaluate the effectiveness of a specific chemoprevention strategy using 5-alpha-reductase inhibitors to reduce the risk of cancer progression while addressing concerns such as anxiety and decisional conflict among patients. Participants will be monitored for changes in their cancer status and any potential side effects from the treatment. The goal is to provide a tailored approach that empowers patients to make informed decisions about their health.
Who could benefit from this research
Good fit: Ideal candidates for this research are men diagnosed with low-grade prostate adenocarcinoma who are currently on active surveillance.
Not a fit: Patients with high-grade prostate cancer or those who have already undergone treatment may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could help men with low-grade prostate cancer manage their condition more effectively and reduce the need for unnecessary treatments.
How similar studies have performed: Previous research has shown promise in using chemoprevention strategies for prostate cancer, although this specific approach is still being evaluated.
Where this research is happening
Tampa, United States
- H. Lee Moffitt Cancer Ctr & Res Inst — Tampa, United States (Active)
Researchers
- Principal investigator: Kumar, Nagi B. — H. Lee Moffitt Cancer Ctr & Res Inst
- Study coordinator: Kumar, Nagi B.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.