Investigating a specific type of retinal cell involved in visual processing
Official title: Genetic analysis of the Robo3+ glycinergic amacrine cell
Funded at Oregon Health & Science University · NIH-10938612 · Data updated 2026-11-12
This study is looking at a special type of cells in the eye that help us see, to learn more about how they work and how they might be involved in vision problems, which could help find new ways to treat these issues.
Quick facts
| Grant type | Fellowship grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Oregon Health & Science University NIH-funded |
| Lab location | 1 site (Portland, United States) |
| Project start | September 15, 2023 |
| Project end | September 14, 2026 |
| Funding year | 2024 |
| Award (this year) | $51,974 |
| NIH project number | 5F31EY035538-02 |
| Project ID | NIH-10938612 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals with genetic conditions affecting retinal function or those experiencing unexplained visual impairments.
✕Less likely to help
Patients with conditions unrelated to retinal function or those who do not have visual processing issues may not benefit from this research.
What this research studies
This research focuses on understanding a subtype of amacrine cells in the retina, which play a crucial role in visual processing. By using advanced techniques such as mouse genetics and various microscopy methods, the researchers aim to isolate and study these cells to uncover their functions and contributions to visual circuits. The project seeks to fill gaps in knowledge about how different retinal cells interact and influence vision, particularly through glycinergic signaling. This could lead to a better understanding of visual disorders and potential therapeutic targets.
Why it matters
Potential benefit: If successful, this research could enhance our understanding of visual processing and lead to new treatments for visual disorders.
How similar studies have gone: Previous research has successfully utilized similar genetic and microscopy techniques to study retinal cells, indicating a promising approach.
Where this research is happening
-
Oregon Health & Science University
Portland, United States Active
Researchers
- Principal investigator: Menn, Arielle — Oregon Health & Science University
- Study coordinator: Menn, Arielle
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.