Investigating a receptor's role in pancreatic cancer spread
Receptor for hyaluronan-mediated motility isoform B (RHAMM B) in Pancreatic Cancer Metastasis
This study is looking at how a specific protein called RHAMM B helps pancreatic cancer spread, with the goal of finding new ways to treat patients with this type of cancer.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Weill Medical Coll of Cornell Univ NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project ID | NIH-10889137 on NIH RePORTER |
What this research studies
This research focuses on understanding how the Receptor for hyaluronan-mediated motility isoform B (RHAMM B) contributes to the spread of pancreatic cancer, particularly pancreatic ductal adenocarcinoma (PDAC). The study aims to explore the mechanisms by which RHAMM B influences cancer cell movement and invasion, using advanced cell culture techniques and signaling pathway analysis. By examining the effects of RHAMM B on cancer cell behavior, researchers hope to identify new therapeutic targets that could improve treatment outcomes for patients with pancreatic cancer.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with pancreatic ductal adenocarcinoma or pancreatic neuroendocrine tumors.
Not a fit: Patients with non-cancerous conditions or those with other types of cancer unrelated to pancreatic cancer may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new therapies that significantly improve survival rates for patients with pancreatic cancer.
How similar studies have performed: Previous research has shown promising results in targeting similar pathways in cancer metastasis, indicating potential for success in this novel approach.
Where this research is happening
New York, United States
- Weill Medical Coll of Cornell Univ — New York, United States (Active)
Researchers
- Principal investigator: Du, Yi-Chieh Nancy — Weill Medical Coll of Cornell Univ
- Study coordinator: Du, Yi-Chieh Nancy
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.