Investigating a receptor's role in bone health and brain diseases.
BLRD Research Career Scientist Award Application
This study is looking at how a special receptor in the body affects bone health and brain conditions, with the goal of creating new treatments for osteoporosis and dementia that could help improve your overall well-being.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Veterans Affairs Med Ctr San Francisco NIH-funded |
| Lab location | 1 site (San Francisco, United States) |
| Project ID | NIH-11031905 on NIH RePORTER |
What this research studies
This research focuses on the calcium-sensing receptor (CaSR) and its impact on bone health and brain diseases. It explores how CaSR regulates mineral and skeletal homeostasis, as well as its potential role in neurodegeneration and dementia. The research aims to develop new treatment regimens for osteoporosis and dementia by leveraging the receptor's actions, with promising preclinical results leading to plans for clinical trials. Patients may benefit from innovative therapies that target both bone and brain health.
Who could benefit from this research
Good fit: Ideal candidates include individuals with osteoporosis, dementia, or other aging-related diseases.
Not a fit: Patients with acute brain injuries or those not affected by osteoporosis or neurodegenerative conditions may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new treatments for osteoporosis and neurodegenerative diseases, improving patient outcomes.
How similar studies have performed: Previous research has shown promise in targeting the CaSR for treating bone-related conditions, indicating potential for success in this novel approach.
Where this research is happening
San Francisco, United States
- Veterans Affairs Med Ctr San Francisco — San Francisco, United States (Active)
Researchers
- Principal investigator: Chang, Wenhan — Veterans Affairs Med Ctr San Francisco
- Study coordinator: Chang, Wenhan
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.