Investigating a receptor involved in Alzheimer's disease
Official title: Chemical Tools to Target TREM2 in Alzheimer's Disease
Funded at Wichita State University · NIH-10869791 · Data updated 2026-11-12
This study is looking at a special protein called TREM2 to see how it works in Alzheimer's disease, with the goal of finding new ways to treat the condition.
Quick facts
| Grant type | R15 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Wichita State University NIH-funded |
| Lab location | 1 site (Wichita, United States) |
| Project start | February 1, 2023 |
| Project end | January 31, 2026 |
| Funding year | 2023 |
| Award (this year) | $49,950 |
| NIH project number | 3R15AG080493-01S1 |
| Project ID | NIH-10869791 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals diagnosed with Alzheimer's disease or those at risk of developing it.
✕Less likely to help
Patients with other forms of dementia unrelated to Alzheimer's may not benefit from this research.
What this research studies
This research focuses on understanding the role of a specific receptor, TREM2, in Alzheimer's disease. Researchers aim to develop new chemical tools to study how TREM2 functions and its potential as a therapeutic target. The project involves creating synthetic methods to produce TREM2 and developing probes to identify its receptors and activation mechanisms. By gaining insights into TREM2, the research hopes to pave the way for new treatment strategies for Alzheimer's disease.
Why it matters
Potential benefit: If successful, this research could lead to new therapeutic strategies for treating Alzheimer's disease.
How similar studies have gone: Previous studies have shown promise in targeting TREM2 for Alzheimer's treatment, indicating potential for success in this approach.
Where this research is happening
-
Wichita State University
Wichita, United States Active
Researchers
- Principal investigator: Wu, Haifan — Wichita State University
- Study coordinator: Wu, Haifan
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.