Investigating a protein's role in energy production within cells
Official title: Aim32, a multi-faceted redox protein, in mitochondrial biogenesis
Funded at Loyola Marymount University · NIH-10974233 · Data updated 2026-11-12
This study is looking at how a protein called Aim32 helps our cells make energy by working with other proteins in the mitochondria, which are like tiny power plants in our cells, and it could help us understand more about energy production and its link to different health issues.
Quick facts
| Grant type | R15 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Loyola Marymount University NIH-funded |
| Lab location | 1 site (Los Angeles, United States) |
| Project start | September 1, 2019 |
| Project end | August 31, 2027 |
| Funding year | 2024 |
| Award (this year) | $431,700 |
| NIH project number | 2R15GM134451-02 |
| Project ID | NIH-10974233 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals with conditions related to mitochondrial dysfunction or energy metabolism disorders.
✕Less likely to help
Patients with conditions unrelated to mitochondrial function or those who do not exhibit symptoms of energy metabolism disorders may not benefit from this research.
What this research studies
This research focuses on understanding how a specific protein, Aim32, influences the production of energy in cells by regulating other proteins involved in mitochondrial function. Mitochondria, the energy factories of cells, rely on a complex system of proteins to perform their functions, and Aim32 is believed to play a crucial role in this process. By studying how Aim32 interacts with these proteins, researchers aim to uncover new insights into cellular energy production and its implications for various diseases. This research employs advanced biochemical techniques to analyze protein interactions and their effects on mitochondrial health.
Why it matters
Potential benefit: If successful, this research could lead to new therapeutic strategies for diseases linked to mitochondrial dysfunction.
How similar studies have gone: Previous research has shown promising results in understanding mitochondrial proteins and their roles, indicating that this approach has potential for significant findings.
Where this research is happening
-
Loyola Marymount University
Los Angeles, United States Active
Researchers
- Principal investigator: Dabir, Deepa Vinay — Loyola Marymount University
- Study coordinator: Dabir, Deepa Vinay
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.