Investigating a protein's role in chronic pain sensitivity
Role of Scn1b in Susceptibility to Neuropathic Pain
This study is looking at how a specific protein might affect why some people experience more neuropathic pain than others, with the goal of finding new ways to help manage this tough condition better.
Quick facts
| Grant type | R21 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California Berkeley NIH-funded |
| Lab location | 1 site (Berkeley, United States) |
| Project ID | NIH-10846155 on NIH RePORTER |
What this research studies
This research focuses on understanding how the SCN1B protein influences susceptibility to neuropathic pain, a chronic condition that significantly impacts many individuals. By studying genetic variations in mouse models, the researchers aim to uncover the mechanisms that contribute to different pain experiences among individuals. The project seeks to identify potential therapeutic targets and biomarkers that could lead to better treatments for neuropathic pain. This work is crucial as current pain management strategies are often ineffective.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals suffering from neuropathic pain or those who have experienced nerve injuries.
Not a fit: Patients with acute pain conditions unrelated to neuropathic pain may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new treatments that more effectively manage or prevent neuropathic pain.
How similar studies have performed: Previous research has shown promise in exploring genetic factors related to pain sensitivity, making this approach both relevant and potentially impactful.
Where this research is happening
Berkeley, United States
- University of California Berkeley — Berkeley, United States (Active)
Researchers
- Principal investigator: Lumpkin, Ellen a — University of California Berkeley
- Study coordinator: Lumpkin, Ellen a
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.