Investigating a protein's role in breast cancer progression and treatment

Who could benefit from this research

What this research studies

This research focuses on understanding how a specific protein, HSPD1, is involved in the progression of breast cancer, particularly in its metastatic form. Using a novel technique, researchers have identified phage ligands that bind selectively to breast cancer cells that have undergone a transition associated with increased aggressiveness. The study aims to explore the relationship between HSPD1 expression and the severity of breast cancer, potentially leading to new imaging and therapeutic strategies that target this protein. Patients may benefit from insights that could improve treatment options and outcomes for breast cancer.

Why it matters

Where this research is happening

• Tuskegee University
  Tuskegee Institute, United States Active

Researchers

• Principal investigator: Bedi, Deepa — Tuskegee University
• Study coordinator: Bedi, Deepa

Related research

Other NIH-funded projects on the same topics.

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  NIH research Icahn School of Medicine at Mount Sinai · New York, United States · NIH-11625517

• Genomic study to understand how genetics and epigenetics shape triple-negative breast cancer in African ancestry

  This study looks at how inherited genes and gene activity affect triple-negative breast cancer in people of African ancestry to better understand why outcomes can be worse.

  NIH research Tuskegee University · Tuskegee Institute, United States · NIH-11621786

• Pragmatic midodrine trial to reduce ICU vasopressor use in septic shock

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• Translational breast cancer research to improve treatment options

  A comprehensive program at Baylor College of Medicine is focusing on breast cancer; researchers will advance targeted therapies and biomarkers to help patients with aggressive or hard-to-treat forms.

  NIH research Baylor College of Medicine · Houston, United States · NIH-11616352

About this research

1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.