Investigating a protein network related to Alzheimer's disease
Functional validation of the SMOC1 matrisomal protein network in Alzheimers disease
This study is looking at certain proteins in the brain to better understand Alzheimer's disease, with the hope that what we learn can help create better treatments for people living with this condition.
Quick facts
| Grant type | Career grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Baylor College of Medicine NIH-funded |
| Lab location | 1 site (Houston, United States) |
| Project ID | NIH-11013864 on NIH RePORTER |
What this research studies
This research focuses on understanding the biology of Alzheimer's disease by examining a specific protein network associated with the condition. The approach involves identifying and characterizing key proteins that contribute to the progression of Alzheimer's, using advanced techniques to analyze how these proteins interact and behave under different conditions. The research also aims to discover new therapeutic targets by exploring proteins linked to Alzheimer's triggers across different species. Patients may benefit from the insights gained, which could lead to improved treatments for Alzheimer's disease.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals aged 21 and older who are affected by or at risk for Alzheimer's disease.
Not a fit: Patients with early-stage cognitive impairment not related to Alzheimer's disease may not receive benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new therapeutic strategies for treating Alzheimer's disease.
How similar studies have performed: Previous research has shown promise in understanding protein networks in Alzheimer's disease, indicating that this approach could yield valuable insights.
Where this research is happening
Houston, United States
- Baylor College of Medicine — Houston, United States (Active)
Researchers
- Principal investigator: Li-Kroeger, David Edward — Baylor College of Medicine
- Study coordinator: Li-Kroeger, David Edward
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.