Investigating a peptide that targets blood vessel growth in the eye.
Integrin-binding Peptide for Ocular Neovascularization and Macular Edema: Molecular Mechanism of Action
This study is looking at a special protein that might help treat eye problems like swelling and abnormal blood vessel growth, which can cause vision loss, to see if it can improve the way these conditions are managed for patients.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Johns Hopkins University NIH-funded |
| Lab location | 1 site (Baltimore, United States) |
| Project ID | NIH-10981081 on NIH RePORTER |
What this research studies
This research focuses on a specific peptide that binds to integrins, which are proteins involved in cell signaling and communication. The study aims to understand how this peptide can help manage ocular neovascularization and macular edema, conditions that can lead to vision loss. By exploring the molecular mechanisms of action, the research seeks to identify how this treatment could improve outcomes for patients with these eye conditions. The approach includes both laboratory studies and potential clinical applications to evaluate effectiveness in human patients.
Who could benefit from this research
Good fit: Ideal candidates for this research are patients suffering from conditions like diabetic retinopathy or other forms of ocular neovascularization.
Not a fit: Patients with non-vascular related eye conditions or those who do not have ocular neovascularization may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new treatments that prevent vision loss in patients with ocular neovascularization and macular edema.
How similar studies have performed: Previous research has shown promise in targeting similar pathways for treating ocular conditions, indicating a potential for success with this approach.
Where this research is happening
Baltimore, United States
- Johns Hopkins University — Baltimore, United States (Active)
Researchers
- Principal investigator: Campochiaro, Peter a — Johns Hopkins University
- Study coordinator: Campochiaro, Peter a
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.