Investigating a new type of T cell involved in allergy and asthma
Role of a Novel Interferon Responsive T Cell Subset in Allergy and Asthma
This study is looking at a special type of immune cell that reacts to allergens to better understand how they affect asthma and allergies, and it's for anyone interested in learning more about how these cells might help us find new ways to treat allergic reactions.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | San Diego Biomedical Research Institute NIH-funded |
| Lab location | 1 site (San Diego, United States) |
| Project ID | NIH-11138363 on NIH RePORTER |
What this research studies
This research focuses on understanding a novel subset of T cells that respond to allergens, particularly in the context of asthma and allergies. By analyzing the genetic profiles of T cells from individuals with and without allergies, the researchers aim to uncover how these cells contribute to airway inflammation. The study involves examining a large number of allergen-reactive T cells to identify differences in their behavior and characteristics, which could lead to new insights into allergy mechanisms and potential treatments.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals with asthma or allergies, particularly those reacting to common allergens like house dust mites.
Not a fit: Patients who do not have asthma or allergies may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new therapeutic strategies for managing allergies and asthma.
How similar studies have performed: Other research has shown promise in understanding T cell responses in allergies, but the specific focus on this novel T cell subset is relatively new and untested.
Where this research is happening
San Diego, United States
- San Diego Biomedical Research Institute — San Diego, United States (Active)
Researchers
- Principal investigator: Seumois, Gregory — San Diego Biomedical Research Institute
- Study coordinator: Seumois, Gregory
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.