Investigating a new type of immune cell involved in cancer spread
Official title: Defining a novel subset of metastasis-associated monocytes
Funded at University of California, San Francisco · NIH-10912533 · Data updated 2026-11-12
This study is looking at a type of immune cell called monocytes to see how they help cancer spread in the body, with the hope of finding new ways to treat metastatic cancer, which could lead to better treatments for patients like you.
Quick facts
| Grant type | Fellowship grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California, San Francisco NIH-funded |
| Lab location | 1 site (San Francisco, United States) |
| Project start | August 3, 2023 |
| Project end | September 13, 2025 |
| Funding year | 2024 |
| Award (this year) | $45,909 |
| NIH project number | 5F31CA284749-02 |
| Project ID | NIH-10912533 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals diagnosed with metastatic cancer, particularly those with lung metastasis.
✕Less likely to help
Patients with localized cancers that have not spread or those who are not undergoing treatment for metastatic disease may not benefit from this research.
What this research studies
This research focuses on understanding a specific group of immune cells called monocytes that play a role in the spread of cancer to other parts of the body. By examining how these cells behave and their metabolic processes, the study aims to uncover new therapeutic targets for treating metastatic cancer. The research will utilize advanced techniques, including single-cell transcriptomics, to analyze the unique characteristics of these monocyte subsets in the context of lung metastasis. Patients may benefit from insights that could lead to more effective treatments for metastatic cancers.
Why it matters
Potential benefit: If successful, this research could lead to new therapies that specifically target the immune mechanisms involved in cancer metastasis.
How similar studies have gone: Previous research has shown promise in targeting immune cells in cancer treatment, indicating that this approach may yield valuable insights.
Where this research is happening
-
University of California, San Francisco
San Francisco, United States Active
Researchers
- Principal investigator: Superville, Daphne a — University of California, San Francisco
- Study coordinator: Superville, Daphne a
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.