Investigating a new treatment to reduce cognitive issues in breast cancer survivors
MnBuOE as a Novel Chemosensitizer for Breast Cancer and Neuroprotector
This study is looking at how chemotherapy can affect thinking and memory in breast cancer patients and is testing a new antioxidant that might help protect the brain from these effects, with the hope of improving life for cancer survivors.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Univ of Arkansas for Med Scis NIH-funded |
| Lab location | 1 site (Little Rock, United States) |
| Project ID | NIH-10894221 on NIH RePORTER |
What this research studies
This research focuses on understanding how chemotherapy affects cognitive function in breast cancer patients and aims to explore a novel antioxidant, MnBuOE, that may help prevent cognitive decline associated with cancer treatment. Using a mouse model, the study will examine the impact of chemotherapy on brain function and how oxidative stress contributes to cognitive impairment. The goal is to identify potential therapeutic strategies that could improve the quality of life for cancer survivors by mitigating cognitive dysfunction.
Who could benefit from this research
Good fit: Ideal candidates for this research are breast cancer patients who are undergoing or have undergone chemotherapy and are experiencing cognitive difficulties.
Not a fit: Patients who are not undergoing chemotherapy or do not have cognitive impairments related to cancer treatment may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new treatments that help preserve cognitive function in breast cancer survivors undergoing chemotherapy.
How similar studies have performed: Previous research has indicated that antioxidants may help mitigate cognitive decline in various contexts, suggesting potential for success in this novel approach.
Where this research is happening
Little Rock, United States
- Univ of Arkansas for Med Scis — Little Rock, United States (Active)
Researchers
- Principal investigator: Allen, Antino Recio — Univ of Arkansas for Med Scis
- Study coordinator: Allen, Antino Recio
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.