Investigating a new treatment for glioblastoma using biomarkers and bioinformatics.
Biomarker, Bioinformatics and Biorepository Core
This study is testing a new treatment called 6-thio-dG for people with glioblastoma, a type of brain tumor, to see how well it works and help improve their care.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Duke University NIH-funded |
| Lab location | 1 site (Durham, United States) |
| Project ID | NIH-10919209 on NIH RePORTER |
What this research studies
This research focuses on developing a novel treatment called 6-thio-dG for patients with glioblastoma, a type of brain tumor. The project involves pre-clinical development and an early-phase clinical trial to assess the treatment's effectiveness. The Biomarker, Bioinformatics and Biorepository Core will provide essential support by standardizing tissue collection protocols and analyzing biomarkers to determine patient eligibility and tumor response. Patients will benefit from a centralized resource that enhances the research process and optimizes treatment outcomes.
Who could benefit from this research
Good fit: Ideal candidates for this research are adults aged 21 and older diagnosed with glioblastoma.
Not a fit: Patients with other types of brain tumors or those under 21 years old may not receive benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved treatment options for patients with glioblastoma.
How similar studies have performed: Other research has shown promise in using biomarker-driven approaches for glioblastoma treatment, indicating potential success for this novel method.
Where this research is happening
Durham, United States
- Duke University — Durham, United States (Active)
Researchers
- Principal investigator: Mclendon, Roger E — Duke University
- Study coordinator: Mclendon, Roger E
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.