Investigating a new target for treating obesity-related insulin resistance

Who could benefit from this research

What this research studies

This research explores the role of thromboxane A2 (TXA2) and its receptor (TP-R) in obesity and insulin resistance. It aims to understand how TP-R influences metabolic pathways, particularly in adipose tissue, which is crucial for fat storage and amino acid metabolism. By studying the effects of TP-R on inflammation and insulin sensitivity, the research seeks to identify potential therapeutic targets for improving metabolic health in individuals with obesity. The study will utilize clinical, biochemical, and molecular methods to gather comprehensive data on these mechanisms.

Why it matters

Where this research is happening

• Omaha VA Medical Center
  Omaha, United States Active

Researchers

• Principal investigator: Viswanathan, Saraswathi — Omaha VA Medical Center
• Study coordinator: Viswanathan, Saraswathi

Related research

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About this research

1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.