Investigating a new target for pain relief
FABP5: Novel Functions in Pain Modulation
This study is looking at how a protein called FABP5 affects pain and aims to create new pain relief options that don't involve addictive opioids, helping people with chronic pain feel better naturally.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | State University New York Stony Brook NIH-funded |
| Lab location | 1 site (Stony Brook, United States) |
| Project ID | NIH-11043378 on NIH RePORTER |
What this research studies
This research focuses on understanding the role of fatty acid binding protein 5 (FABP5) in pain modulation. The team aims to develop non-opioid analgesics that can effectively manage chronic pain without the risk of addiction associated with current opioid treatments. By inhibiting FABP5, they hope to enhance the levels of natural pain-relieving compounds in the body and reduce inflammation that contributes to pain. The research includes preclinical testing of new FABP5 inhibitors, with plans for clinical trials in the near future.
Who could benefit from this research
Good fit: Ideal candidates for this research are adults experiencing chronic pain who are seeking alternatives to opioid medications.
Not a fit: Patients who do not experience chronic pain or have conditions unrelated to pain management may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to safer and more effective pain management options for patients suffering from chronic pain.
How similar studies have performed: Other research has shown promising results with similar approaches targeting lipid transport mechanisms for pain relief, indicating potential for success in this area.
Where this research is happening
Stony Brook, United States
- State University New York Stony Brook — Stony Brook, United States (Active)
Researchers
- Principal investigator: Kaczocha, Martin — State University New York Stony Brook
- Study coordinator: Kaczocha, Martin
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.