Investigating a new protein to treat fatty liver disease
Resolution of nonalcoholic fatty liver and nonalcoholic steatohepatitis by a novel adipokine
This study is looking at a new protein that might help reduce fat and inflammation in the liver for people with nonalcoholic steatohepatitis (NASH), with the hope of finding better treatments for this condition.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Univ of Massachusetts Med Sch Worcester NIH-funded |
| Lab location | 1 site (Worcester, United States) |
| Project ID | NIH-10940348 on NIH RePORTER |
What this research studies
This research focuses on nonalcoholic steatohepatitis (NASH), a serious liver condition caused by fat buildup in the liver. The study aims to explore a novel protein that has shown promise in reducing liver fat and inflammation in animal models. Researchers will evaluate how this protein works in the body and its potential to improve liver health. By understanding the mechanisms involved, the team hopes to pave the way for new treatments for patients suffering from NASH.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with nonalcoholic steatohepatitis or related liver conditions.
Not a fit: Patients with liver diseases caused by alcohol consumption or other non-metabolic factors may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to effective therapies for patients with nonalcoholic fatty liver disease and NASH.
How similar studies have performed: Previous research has shown promise in targeting similar pathways for liver disease treatment, indicating potential for success in this novel approach.
Where this research is happening
Worcester, United States
- Univ of Massachusetts Med Sch Worcester — Worcester, United States (Active)
Researchers
- Principal investigator: Wang, Yong-Xu — Univ of Massachusetts Med Sch Worcester
- Study coordinator: Wang, Yong-Xu
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.