Investigating a new protein that regulates heart energy and function
Perm1 is a Novel Regulator of Cardiac Energetics and Function
This study is looking at a new protein called Perm1 to see how it affects heart energy and function, which could help us find better treatments for heart disease that might benefit patients like you.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Virginia Polytechnic Inst and St Univ NIH-funded |
| Lab location | 1 site (Blacksburg, United States) |
| Project ID | NIH-10886220 on NIH RePORTER |
What this research studies
This research focuses on understanding how a novel protein, Perm1, influences the energy production and overall function of the heart. By examining the role of Perm1 in cardiac cells, the study aims to uncover its effects on mitochondrial function and how it responds to physical stress. The approach involves detailed analysis of cellular signaling pathways and gene expression related to heart health, which could lead to new insights into heart disease mechanisms. Patients may benefit from this research as it could pave the way for innovative treatments targeting heart function.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals with heart disease or those at risk of developing cardiac conditions.
Not a fit: Patients without any cardiac issues or those who do not have risk factors for heart disease may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new therapies that improve heart function and energy metabolism in patients with heart disease.
How similar studies have performed: Other research has shown promising results in understanding cardiac signaling pathways, suggesting that this approach could yield valuable insights.
Where this research is happening
Blacksburg, United States
- Virginia Polytechnic Inst and St Univ — Blacksburg, United States (Active)
Researchers
- Principal investigator: Warren, Junko Shibayama — Virginia Polytechnic Inst and St Univ
- Study coordinator: Warren, Junko Shibayama
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.