Investigating a new protein that helps heart cells function and grow
Official title: C5ORF51 - a Novel Regulator of Cardiomyocyte Function and Homeostasis
Funded at University of Maryland Baltimore · NIH-11192962 · Data updated 2026-11-12
This study is looking at a new protein called C5ORF51 to see how it affects heart cells, especially after heart attacks, and it aims to find ways to help improve heart recovery and health for people with heart problems.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Maryland Baltimore NIH-funded |
| Lab location | 1 site (Baltimore, United States) |
| Project start | September 26, 2024 |
| Project end | August 31, 2025 |
| Funding year | 2024 |
| Award (this year) | $678,445 |
| NIH project number | 1R56HL169267-01A1 |
| Project ID | NIH-11192962 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are adults with cardiovascular diseases or those at risk of heart-related conditions.
✕Less likely to help
Patients with non-cardiovascular diseases or those who are not adults may not benefit from this research.
What this research studies
This research focuses on understanding how a novel protein, C5ORF51, influences the function and growth of heart cells, known as cardiomyocytes. The study aims to uncover the mechanisms by which C5ORF51 regulates heart cell behavior, particularly after events like heart attacks, which often lead to severe cardiovascular issues. By using both laboratory models and genetic analysis, the researchers will explore how this protein affects heart cell development and overall heart health. The findings could provide insights into improving heart recovery and function in patients with cardiovascular diseases.
Why it matters
Potential benefit: If successful, this research could lead to new treatments that enhance heart cell recovery and function after heart attacks.
How similar studies have gone: Other research has shown promise in understanding cardiac function through similar molecular approaches, indicating potential for success in this area.
Where this research is happening
-
University of Maryland Baltimore
Baltimore, United States Active
Researchers
- Principal investigator: Liu, Ruya — University of Maryland Baltimore
- Study coordinator: Liu, Ruya
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.